Stability of octreotide acetate decreases in a sodium bisulfate concentration-dependent manner: compatibility study with morphine and metoclopramide injections

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Stability of octreotide acetate decreases in a sodium bisulfate concentration-dependent manner: compatibility study with morphine and metoclopramide injections

PURPOSE Sodium bisulfate is known to affect the stability of octreotide. However, the critical concentration of sodium bisulfate is not known. Therefore, we assessed the critical concentration of sodium bisulfate needed to preserve the stability of octreotide using actual drugs containing sodium bisulfate. METHODS Although morphine and metoclopramide preparations are considered to be compatib...

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ژورنال

عنوان ژورنال: European Journal of Hospital Pharmacy

سال: 2015

ISSN: 2047-9956,2047-9964

DOI: 10.1136/ejhpharm-2014-000555